The objective of this study was to compare genetic gain, aggregate genotype and change of inbreeding in closed nucleus, open nucleus and sire referencing strategies with computer simulation. Four traits of litter size (LS), weaning weight (WW), average daily gain from weaning to 6 months of age (ADG) and greasy fleece weight (GFW) were included in selection index and breeding goal. Relative economic values of these traits were 240, 8, 0.424 and 1, respectively. The genetic gain, aggregate genotype and inbreeding for three strategies were calculated for 10 years selection. Average and standard errors of 20 repeats were reported. Results of simulation showed that cumulative genetic gain in closed nucleus after 10 years selection was 0.190, 1.342 kg, 44.96 g and 0.125 kg for LS, WW, ADG and GFW, respectively. These estimates were 0.193, 1.355 kg, 46.50 g and 0.128 kg in open nucleus and 0.197; 1.492 kg, 52.48 g and 0.138 kg in sire referencing strategies, respectively. For all traits, genetic gain resulted from sire referencing strategy were higher than closed and open nucleus strategies. Average yearly increase of inbreeding coefficient were 0.247, 0.095 and 0.175 percentage for closed nucleus, open nucleus and sire referencing strategies, respectively. Inbreeding coefficient in open nucleus was lower than closed nucleus and sire referencing strategies. In general, based on genetic gain and aggregate genotype value, sire referencing strategy is more suitable than open and closed nucleus strategies for Baluchi sheep breeding.